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Should Eye Drops be kept in the fridge? Keep your eye drops in the refrigerator. (Note: Most eye drops are fine to store at temperatures between 40 and 60 degrees Fahrenheit once they are opened.) This way, you can feel the cool drop as it falls onto your skin. Can brimonidine cause high blood pressure? Severe cardiovascular (heart) disease: Although brimonidine typically has little effect on blood pressure and heart rate, it may lower blood pressure and heart rate (pulse) if you have severe heart disease. What are the side effects of eye drops? Side Effects. Stinging/redness in the eye, widened pupils, or blurred vision may occur.
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