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Can Orencia cause hair loss? "Maybe 1 or 2 people out of 10 who take it will get hair loss," estimates Dr. Husni. Another DMARD, Arava (leflunomide), can sometimes also cause hair loss as a side effect. In extremely rare cases, biologic medications like Humira (adalimumab) or Enbrel (etanercept) can also have this side effect.
What pain reliever can you take with methotrexate? In that case, taking an aspirin or other nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen or naproxen at the same time may be an option.
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