Can you have sepsis without knowing? But sepsis can also develop with influenza (the flu), an infected cut or scrape, or strep throat, to name a few. It's clear that sepsis doesn't occur without an infection in your body, but it is possible that someone develops sepsis without realizing they had an infection in the first place. How do antibiotics work against bacteria? Antibiotics work by affecting things that bacterial cells have but human cells don't. For example, human cells do not have cell walls, while many types of bacteria do. The antibiotic penicillin works by keeping a bacterium from building a cell wall. Some antibiotics dissolve the membrane of just bacterial cells.
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