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What happens if strep is not treated with antibiotics? Complications of strep throat are rare but can occur, especially if your throat infection isn't properly treated with antibiotics. Complications can also result in your immune system attacking itself and causing serious conditions such as rheumatic fever. Why would an infection not respond to antibiotics? Each time you take an antibiotic, bacteria are killed. Sometimes, bacteria causing infections are already resistant to prescribed antibiotics. Resistant bacteria do not respond to the antibiotics and continue to cause infection. A common misconception is that a person's body becomes resistant to specific medicines. Can your body heal an infection on its own? Infection of the wound triggers the body's immune response, causing inflammation and tissue damage, as well as slowing the healing process. Many infections will be self-contained and resolve on their own, such as a scratch or infected hair follicle.
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