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Can chlorthalidone cause kidney problems? Many patients who have high blood pressure will not notice any signs of the problem. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Chlorthalidone is usually taken in the morning with food.
Is tramadol safe for kidney patients? Tramadol. Tramadol is generally preferred for moderate pain in CKD patients because it is not known to be directly nephrotoxic. Nonetheless, it must be noted that its systemic elimination is reduced with advanced CKD (GFR <30 ml/min/1.73 m 2).
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