Can thyroid cause respiratory problems? In addition, hypothyroidism can cause mild high blood pressure and raise blood levels of cholesterol. Respiratory system — Hypothyroidism weakens the respiratory muscles and decreases lung function. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. What is a goiter and what causes it? The most common cause of goiters worldwide is a lack of iodine in the diet. In the United States, where the use of iodized salt is common, a goiter is more often due to the over- or underproduction of thyroid hormones or to nodules that develop in the gland itself.
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