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What is the toxic metabolite of paracetamol? When taken in overdose the liver conjugation becomes inundated, causing paracetamol to be metabolised by an alternative pathway. This results in a toxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI), which is itself inactivated by glutathione, rapidly preventing any harm.
What is the best cold and flu medicine? Our Top Picks Theraflu Multi-Symptom Severe Cold Green Tea & Honey Lemon. Tylenol Cold + Head Congestion Severe. Genexa Multi-Symptom Cold Relief. Sambucol Black Elderberry Cold & Flu Relief Tablets. Mucinex Sinus-Max Pressure and Pain Caplets. Vicks DayQuil Cough Cold and Flu Relief.
What can I take for body aches and chills? The flu may cause chills even before a fever develops. Wrapping yourself in a warm blanket can increase your body temperature and possibly reduce chills. If you have body aches, you can take over-the-counter pain relieving medication, such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin).
Who is at high risk for flu complications? Older adults (above 65 years) According to the CDC, people aged 65 and older are at a greater risk for serious complications from the flu. This is because the immune system typically weakens with age. Flu infection can also worsen long-term health conditions, like heart disease, lung disease, and asthma.
What makes the flu deadly? Influenza is commonly called the flu, but it's not the same as stomach " flu " viruses that cause diarrhea and vomiting. For most people, influenza resolves on its own. But sometimes, influenza and its complications can be deadly.
When should I be concerned about flu symptoms? Most people who have the flu (influenza) have a mild illness and don't need to see a doctor. Common flu signs and symptoms include: Fever above 100 F (38 C), though not everyone with the flu has a fever. A cough or sore throat.
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