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Can ursodiol affect the liver? In addition, ursodiol has been shown to decrease serum enzyme elevations in a large number of cholestatic liver diseases including primary biliary cirrhosis, the cholestasis of pregnancy, and parenteral nutrition associated liver disease.
Can you take ursodiol without food? It is best to take ursodiol with meals, unless otherwise directed by your doctor. Take this medicine for the full time of treatment, even if you begin to feel better. If you stop taking this medicine too soon, the gallstones may not dissolve as fast or may not dissolve at all.
Can you have PBC with normal liver function tests? Liver Function Tests. Patients with PBC have abnormal liver function tests, usually the alkaline phosphatase is more raised than the transaminases. Serum bilirubin is elevated late in the disease. Liver synthetic function is preserved until late in the disease, so serum albumin and clotting are usually normal.
Is primary biliary cirrhosis reversible? It's not curable, and over time it can lead to permanent liver damage. However, PBC usually develops slowly. That means you may be able to live normally for many years without any symptoms.
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