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How does ACE inhibitor reduce proteinuria? Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) reduce intraglomerular pressure by inhibiting angiotensin II М¶ mediated efferent arteriolar vasoconstriction. These drugs also have a proteinuria - reducing effect that is independent of their antihypertensive effect.
Does minimal change disease go away? Minimal Change Disease is one of the more treatable kidney diseases, especially in children. A complete remission is not uncommon, though the disease can come back later in life. Patients with recurrent MCD, or with MCD that does not completely resolve with steroids, may require other forms of chemotherapy.
What are the signs and symptoms of proteinuria? In most cases, proteinuria has no symptoms and is detected during a routine screening in people with high blood pressure or diabetes. If protein loss is severe, swelling or edema can occur. Other symptoms can include: Foamy urine. Weight gain caused by fluid retention. Diminished appetite. Hypertension.
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