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What if I miss a day of Chantix? If you miss your regular dose of Chantix (varenicline), take it as soon as you can. If it is almost time for your next dose of Chantix, skip the make-up dose and follow your regular dosing regimen. Never take a double dose of Chantix. Call your doctor with any questions about dosages. Can you use Chantix to quit vaping? While some people may use them to replace cigarettes or in addition to smoking, e-cigarettes are not FDA-approved as an option to help you quit. CHANTIX has not been studied in patients using e-cigarettes and is not indicated for use in these patients. How does smoking affect medication? Tobacco smoke induces many of the CYP450 enzymes in the liver, which play an important role in medication absorption, distribution, metabolism, and elimination. Psychiatric medications such as antipsychotics, antidepressants, hypnotics, and anxiolytics are widely affected by cigarette smoking.
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