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Can a nurse practitioner prescribe antidepressants? Can an NP Prescribe Antidepressants ? Yes! This is a broad category of pharmaceuticals such as SSRIs (e.g., Prozac, Zoloft), MAOIs (e.g., Nardil), and other drugs. Similar to antibiotics, antidepressants are typically non-controlled substances, which comes as a surprise to some people.
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